Endothelial Piezo1: Life depends on it

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Endothelial Piezo1 channels as sensors of exercise

Piezo1 channels are newly discovered ion channels which have come to the fore as players in endothelial biology. They have a key role as sensors of shear stress, a frictional force which arises in vascular biology because of blood flow. Endothelial Piezo1 channels are critical in murine embryonic development, just after the heart starts to beat and drive blood into the nascent endothelial netwo...

متن کامل

It Depends

Context plays a crucial role for semantic similarity measurements. Depending on aspects such as location, time, task and user preferences, the respects that play a role for the comparison of concepts may vary. This variance should be reflected in a change of the similarity measurements’ results. Although this dependency has been observed in various human subject tests and is accounted for in re...

متن کامل

Piezo1

Piezo ion channels have been found to be essential for mechanical responses in cells. These channels were first shown to exist in Neuro2A cells, and the gene was identified by siRNAs that diminished the mechanical response. Piezo channels are approximately 2500 amino acids long, have between 24-32 transmembrane regions, and appear to assemble into tetramers and require no other proteins for act...

متن کامل

Anaphylactic shock depends on endothelial Gq/G11

Anaphylactic shock is a severe allergic reaction involving multiple organs including the bronchial and cardiovascular system. Most anaphylactic mediators, like platelet-activating factor (PAF), histamine, and others, act through G protein-coupled receptors, which are linked to the heterotrimeric G proteins G(q)/G(11), G(12)/G(13), and G(i). The role of downstream signaling pathways activated by...

متن کامل

It All Depends

JULY/AUGUST 2009 ■ 1540-7993/09/$26.00 © 2009 IEEE ■ COPUbLIShEd bY ThE IEEE COmPUTEr And rELIAbILITY SOCIETIES 61 Lori M. KaufMan BAE Systems ers, partners, and vendors. By sharing resources at various levels, this platform offers various services, such as an infrastructure cloud (for example, hardware or IT infrastructure management), a software cloud (such as software, middleware, or traditi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Channels

سال: 2015

ISSN: 1933-6950,1933-6969

DOI: 10.4161/19336950.2014.986623